Camellia powder can be used as a functional food to protect liver damage
Camellia powder can be used as a
functional food to protect liver damage!
Alcoholism is one of the causes of liver disease. In
recent years, due to the increase in drinking frequency and changes in dietary
structure, the incidence of alcoholic liver in China has increased
significantly, and it has become another liver disease that seriously threatens
human health in addition to viral hepatitis, which has drawn great attention
from society. Therefore, it is particularly urgent to find natural
medicines without side effects to prevent and treat liver diseases.
Studies have shown that many natural foods have
hepatoprotective activity, and bee pollen is one of them, such as rapeseed
pollen and masson pine pollen, which have been reported. Bee pollen is a
cake formed by bees collecting pollen from plant anthers and adding a small
amount of saliva after processing. It is known as a "natural nutrition
bank".
Previous studies have shown that bee pollen contains more
than 250 substances, including lipids (triglycerides), fatty acids, amino
acids, vitamins, minerals, phenols, and flavonoids. They have antioxidant,
antibacterial, antiviral, and anti-bacterial properties. Inflammation and
enhance immunity. Therefore, bee pollen has been widely used as a
traditional medicine and health food. Camellia is a kind of bee pollen,
which is mainly produced in China. Because of its characteristics of sweet and
delicious, fresh smell, it is well received by consumers.
Kao et al. 'S research
found that tea pollen has strong antioxidant activity and contains a variety of
phenols and flavonoids, such as gallic acid, ferulic acid, caffeic acid,
catechins, and rutin. Yildiz et al. Proved that polyphenols and flavonoids
in natural foods are related to their liver-protective activities, but so far,
research on the hepatoprotective effects of camellia powder has rarely been
reported.
The School of Food Science and Engineering of Northwest University
and the Shaanxi Bee Product Engineering Technology Research Center have
determined the total phenol and total flavonoid content of tea pollen from five
places. Based on this, the in vitro antioxidant activity of tea pollen and its
effect on alcohol induction were studied. Protective effect of acute liver
injury. The results showed that the total phenol and total flavonoid
content of Zhejiang tea pollen was the highest, being 8.97 mg / g and 3.01 mg /
g, respectively, and had high antioxidant activity. The mice were
continuously administrated with tea pollen for 7 weeks, and their ability to
absorb oxygen free radicals in the serum increased significantly (P <0 .05="" and="" by="" cu2="" damage="" improved="" induced="" lipid="" peroxidation="" significantly="" span="" the="" was="">
Compared with the model group, the activity of aspartate
aminotransferase and alanine aminotransferase in the serum of the tea pollen
group decreased significantly (P <0 .05="" 0.05="" a="" activities="" activity="" acute="" alcohol.="" alcohol="" also="" and="" antioxidant="" as="" be="" but="" by="" camellia="" can="" caused="" cell="" content="" damage="" dismutase="" effects="" food="" functional="" glutathione="" has="" he="" improve="" in="" increased="" indicate="" injury.="" injury="" istopathological="" liver="" malondialdehyde="" material="" nbsp="" not="" observations="" obvious="" of="" on="" only="" peroxidase="" pollen="" powder="" protect="" protective="" raw="" reduced="" results="" showed="" significantly="" span="" strong="" study="" superoxide="" tea="" that="" the="" this="" tissue="" to="" used="" was="">
Bee pollen is famous for its rich nutrients and medicinal
value. In recent years, there have been more and more functional studies
on bee pollen, which has received widespread attention for its functions such
as lowering blood lipids, lowering blood sugar, anti-atherosclerosis, and
treating the prostate. Camellia pollen, as a kind of bee pollen, has a
large output in China and has potential development value, but so far, there
are few functional studies on tea pollen. In this study, a model of acute
alcoholic liver injury was established by injecting alcohol (5.0 g / kg) into
mice at one time to explore the hepatoprotective function of camellia pollen,
which provides a theoretical basis for becoming a new type of health food. Polyphenols
and flavonoids are a class of antioxidants widely present in plants, and play
an important role in the antioxidant activity of natural foods.
This study selected tea pollen from Zhejiang, Anhui,
Jiangxi, Sichuan, and Hunan to determine its total phenol and total flavonoid
content. The results were 8.41 to 8.97 and 2.23 to 3.01 mg / g, respectively.
The results of total phenol and total flavonoid content (8.49, 2.33mg / g) are
almost the same. DPPH free radical scavenging ability and FRAP in vitro
experiment results show that tea pollen has strong antioxidant activity in
vitro and has a very important effect on human health.
In addition, studies have found that Camellia powder can
improve the antioxidative capacity of mice in vivo. The ORAC experiment
demonstrated that the high-dose group's serum inhibited fluorescence quenching
more effectively than the normal group. Similarly, in the experiment of
oxidative injury induced by Cu2 + in mouse serum, compared with the normal
group, the high-dose group can significantly reduce the formation of
lipoprotein oxidation products in the serum, further indicating that tea pollen
can enhance the anti-oxidative ability of mouse serum. The catabolism of
alcohol in the liver will promote the production of reactive oxygen species
(ROS), and excessive accumulation of ROS in the body will cause lipid
peroxidation of liver cell membranes and damage liver cells. AST and ALT
are aminotransferases present in liver cells. When liver cells are damaged, AST
and ALT are released into the blood.
In the study, compared with the normal group, the AST and
ALT activities in the serum of the model group mice were significantly increased
(P <0 .05="" 6.0g="" a="" action="" activities="" activity="" addition="" administration="" after="" all="" also="" alt="" an="" and="" anion="" as="" ast="" be="" body.="" but="" by="" camellia="" can="" catalase="" cell="" contained="" conversion="" damage.="" damage="" decomposed="" degree="" different="" dna="" doses="" enzyme="" fact="" flavonoids="" free="" function="" further="" gsh-px.="" have="" his="" hydrogen="" important="" in="" indirectly="" injury.="" into="" is="" it="" kg="" lipid="" liver="" may="" mda="" mice="" n="" nbsp="" of="" oxidative="" peroxidation="" peroxide.="" peroxide="" pollen="" product="" promote="" radicals="" reduced="" reducing="" reflect="" related="" ros-removing="" rutin="" serum="" significantly="" span="" such="" superoxide="" tea="" that="" the="" their="" to="" water="" were="" with="">
The study found that the activity of SOD and GSH-Px in
the serum of the mice in the model group was significantly reduced, and the MDA
content was significantly increased, indicating that the administration of
alcohol to the mice will significantly damage the body's antioxidant defense
system, leading to the accumulation of ROS and triggering lipid metabolism.
Oxidation. After the mice were administrated with tea pollen, the
activities of SOD and GSH-Px in the mice were significantly enhanced, and the
MDA content was significantly reduced, indicating that the tea pollen can
improve the ability of the mice to resist the oxidative damage of ROS attack on
biofilms and biomacromolecules This may be related to the fact that gallic acid
and caffeic acid in camellia can alleviate inflammation caused by oxidative
stress and enhance the activity of SOD and GSH-Px in mice. In addition,
histopathological staining observations showed that tea pollen can reduce
alcohol-induced liver cell inflammation and infiltration and liver cell death.
To sum up, the content of total phenol and total
flavonoids in tea pollen is rich, and has strong antioxidant activity. In
addition, in vivo experiments in mice have shown that tea pollen can reduce the
activity of AST and ALT in mouse serum, enhance the activity of SOD and GSH-Px
in mice, and reduce the content of lipid peroxide MDA. The results show
that camellia pollen has protective effects on alcohol-induced acute liver
injury. Therefore, camellia can be used as a new type of antioxidant food and
as a raw material for producing liver-protecting functional foods.
Post a Comment